CRISPR’s Expanding Toolkit: Beyond Simple Cuts

The CRISPR-Cas9 system, initially lauded for its gene-editing precision, has rapidly evolved beyond its basic “cut and paste” functionality. Scientists are now leveraging its versatility to perform a wider array of genetic manipulations, moving beyond simple gene knockouts and into more nuanced control of gene expression and even targeted epigenetic modifications. This expanded toolkit opens doors to more sophisticated therapies and a deeper understanding of gene regulation.

Base Editing: Subtle Changes, Significant Impact

One significant advancement is base editing, a technique that allows scientists to make precise single-base changes in DNA without creating a